About Us

We are a digital-healthcare focused venture capital firm that manages capital on behalf of a group of strategic limited partners and commercial investors. Founded by two healthcare veterans, Steven Epstein and Gregory Epstein of Epstein Becker & Green, P.C., Epsilon draws on decades of experience across healthcare investing, advising, providing regulatory support and board leadership. We leverage our strategic LP base and the deep experience and relationships of our founders and advisors to help our portfolio companies achieve scale.

Investment Focus

We take a thematic investment approach with a focus on digital health companies that are addressing large pain points and areas of inefficiency in the healthcare system.


Focused on Seed+ to Series B


Digital health, including healthcare IT and technology-enabled services


Able to lead rounds or invest as a part of a syndicate


We manage capital on behalf of a distinctive group of limited partners, including health systems, health plans, other healthcare organizations, family offices and notable healthcare executives and entrepreneurs, including a former CMS administrator, multiple hospital CEOs and the former chair of the American Hospital Association. Our institutional LPs collectively include:






Provider Locations


Health Plan Members

We provide differentiated strategic support and guidance to our portfolio companies, including through unique industry insight and value-added introductions to our vast healthcare network.